IL-17-话题@MedSci

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IL-17

2020-05-29

侠胆医心 (审核中...)

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全文收起 #OX40##靶点#可能成为#特应性皮炎#新的明星靶点! #OX40L单抗##amlitelimab#的临床试验IIb达到主要终点。此前#Rocatinlimab#同样效果不俗。使得特应性皮炎，从#IL-13#， #IL-17#， #IL-21#等不同的靶点，进一步拓展至OX40L，未来可能对于单一治疗效果不好的病人，可以多药联用，有望取得更好的效果。另外，还有必要开发针对婴幼儿的特应性皮炎的治疗，这是临床刚需。 #湿疹#

OX40靶点可能成为特应性皮炎新的明星靶点! OX40L单抗amlitelimab的临床试验IIb达到主要终点

2023-10-16发表于上海

fzwish20000 (审核中...)

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#IL-17#

Am J Clin Dermatol：IL-12/23、IL-17和IL-23抑制剂治疗银屑病的药物存活率

2022-08-24

fzwish20000 (审核中...)

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#IL-17#

Crit Care：伴有AKI的危重患者血清IL-17水平较高且与患者较差预后相关

2022-04-17

fzwish20000 (审核中...)

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#IL-17#

Front Immunol：IL-17加重慢性阻塞性肺疾病急性加重期铜绿假单胞菌呼吸道感染

2022-03-14

fzwish20000 (审核中...)

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#IL-17#

Br J Dermatol：Brodaluma阻断 IL-17RA可减少化脓性汗腺炎皮肤和血清中的炎症通路

2022-03-06

fzwish20000 (审核中...)

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#IL-17#

UCB正在寻求IL-17A 和 IL-17F 双重抑制剂Bimzelx在银屑病关节炎中的批准

2022-01-25

fzwish20000 (审核中...)

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#IL-17#

J Invest Dermatol：IL-17A产生细胞在皮肤炎性疾病中的调节

2021-10-28

fzwish20000 (审核中...)

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#IL-17#

Arthritis Res Ther：IL-17抑制剂治疗强直性脊柱炎的疗效和安全性如何？

2021-05-05

医者仁心 (审核中...)

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#IL-17#

Lancet：IL-17A/F纳米体索洛奇单抗治疗斑块型银屑病II期临床获得成功

2021-04-28

fzwish20000 (审核中...)

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#IL-17#

BMC Gastroenterology：血浆中IL-17和甲胎蛋白的水平可有效预测肝硬化患者发生肝癌的风险

2021-04-20

fzwish20000 (审核中...)

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#IL-17#

恒瑞 IL-17A单抗SHR-1314用于强直性脊柱炎获批临床试验

2020-11-19

fzwish20000 (审核中...)

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#IL-17#

Can J Cardiol：与环孢素或甲氨蝶呤治疗相比，抑制IL-17A可使血管和心肌功能得到更大的改善

2020-11-15

fzwish20000 (审核中...)

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#IL-17#

诺华的IL-17A单抗Cosentyx在银屑病关节炎III期研究中显著减轻滑膜炎

2020-11-08

fzwish20000 (审核中...)

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#IL-17#

头对头3期临床证实：抗IL-17单抗Bimekizumab治疗中度至重度银屑病优于TNF单抗修美乐

2020-11-04

fzwish20000 (审核中...)

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#IL-17#

J Allergy Clin Immunol：高IL-17型哮喘患者具有银屑病免疫表型

2020-10-02

fzwish20000 (审核中...)

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#IL-17#

诺华IL-17A单抗Cosentyx：获欧盟批准一线治疗牛皮癣儿童患者

2020-08-06

fzwish20000 (审核中...)

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#IL-17#

牛皮癣III期临床：礼来的IL-23单抗mirikizumab优于诺华的IL-17A单抗Cosentyx

2020-07-20

fzwish20000 (审核中...)

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#IL-17#

FDA批准诺华的IL-17A单抗Cosytyx，用于治疗非放射线轴性脊柱关节炎

2020-06-19

fzwish20000 (审核中...)

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#IL-17#

AAD 2020：3期临床证实IL-17A/IL-17F单抗Bimekizumab治疗牛皮癣，优于IL-12/IL-23单抗ustekinumab

2020-06-15

fzwish20000 (审核中...)

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#IL-17#

诺华III期PREVENT研究：IL-17A单抗Cosentyx可持久缓解中轴性脊柱关节炎

2020-06-06

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