2025 CTS临床实践指南：α-1-抗胰蛋白酶缺乏症的靶向检测和强化治疗

2025-04-01 加拿大胸科学会 Chest 发表于上海

本文主要针对α-1-抗胰蛋白酶缺乏症的靶向检测和强化治疗提供循证指导。

中文标题：

英文标题：

Alpha-1-Antitrypsin Deficiency Targeted Testing and Augmentation Therapy: A Canadian Thoracic Society Meta-Analysis and Clinical Practice Guideline

发布机构：

加拿大胸科学会

发布日期：

2025-04-01

简要介绍：

α-1抗胰蛋白酶（A1AT）缺乏症是一种常见的遗传性疾病，与慢性阻塞性肺疾病（COPD）发生的风险增加有关。许多患有严重A1AT缺乏症的人没有被诊断出来，或者被诊断得很晚，无法从疾病特异性咨询和修饰治疗中获益。本文主要针对α-1-抗胰蛋白酶缺乏症的靶向检测和强化治疗提供循证指导。

相关资料下载：

GetToolGuiderByIdResponse(projectId=1, id=13ed81c00a2e7234, title=2025 CTS临床实践指南：α-1-抗胰蛋白酶缺乏症的靶向检测和强化治疗, enTitle=Alpha-1-Antitrypsin Deficiency Targeted Testing and Augmentation Therapy: A Canadian Thoracic Society Meta-Analysis and Clinical Practice Guideline, guiderFrom=Chest, authorId=0, author=, summary=本文主要针对α-1-抗胰蛋白酶缺乏症的靶向检测和强化治疗提供循证指导。, cover=https://img.medsci.cn/20241106/1730861354737_8538692.png, journalId=0, articlesId=null, associationId=394, associationName=加拿大胸科学会, associationIntro=The Canadian Thoracic Society (CTS) promotes lung health by supporting the respiratory community through leadership, collaboration, research, learning and advocacy, and promoting the best respiratory practices in Canada., copyright=0, guiderPublishedTime=Tue Apr 01 00:00:00 CST 2025, originalUrl=, linkOutUrl=, content=<div class="guideDetailsCont flex-row-between-start" style="color: #333333;"> <div class="detailsContRight summary" style="color: #222222;" data-lines="12"><span class="text">α-1抗胰蛋白酶（A1AT）缺乏症是一种常见的遗传性疾病，与慢性阻塞性肺疾病（COPD）发生的风险增加有关。许多患有严重A1AT缺乏症的人没有被诊断出来，或者被诊断得很晚，无法从疾病特异性咨询和修饰治疗中获益。本文主要针对α-1-抗胰蛋白酶缺乏症的靶向检测和强化治疗提供循证指导。</span></div> </div>, tagList=[TagDto(tagId=503520, tagName=α-1-抗胰蛋白酶缺乏症)], categoryList=[CategoryDto(categoryId=12, categoryName=呼吸, tenant=100), CategoryDto(categoryId=85, categoryName=指南&解读, tenant=100)], articleKeywordId=503520, articleKeyword=α-1-抗胰蛋白酶缺乏症, articleKeywordNum=6, guiderKeywordId=503520, guiderKeyword=α-1-抗胰蛋白酶缺乏症, guiderKeywordNum=6, haveAttachments=1, attachmentList=null, guiderType=0, guiderArea=指南, guiderLanguage=1, guiderRegion=6, opened=0, paymentType=, paymentAmount=10, recommend=0, recommendEndTime=null, sticky=0, stickyEndTime=null, allHits=426, appHits=28, showAppHits=0, pcHits=18, showPcHits=398, likes=0, shares=13, comments=0, approvalStatus=1, publishedTime=Mon Apr 14 20:00:00 CST 2025, publishedTimeString=2025-04-01, pcVisible=1, appVisible=1, editorId=0, editor=dajiong, waterMark=0, formatted=0, memberCards=[], isPrivilege=0, deleted=0, version=4, createdBy=null, createdName=dajiong, createdTime=Mon Apr 14 17:23:41 CST 2025, updatedBy=8538692, updatedName=梅斯话题小助手, updatedTime=Mon Apr 14 18:17:49 CST 2025, courseDetails=[], otherVersionGuiders=[], isGuiderMember=false, ipAttribution=上海, attachmentFileNameList=[AttachmentFileName(sort=1, fileName=2025 CTS临床实践指南：α-1-抗胰蛋白酶缺乏症的靶向检测和强化治疗.pdf)])