细胞焦亡-话题@MedSci

#细胞焦亡#

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objectType=article, longId=776977, objectId=73dbe76977a2, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20230615/1686805134351_5610093.png, objectUrl=/article/show_article.do?id=73dbe76977a2, replyNumber=0, likeNumber=132, createdTime=2024-01-29, rootId=0, userName=侠胆医心, userId=f63e4754896, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=加利福尼亚, moduleDTOList=[ModuleDTO(moduleId=73dbe76977a2, moduleTitle=J Ethnopharmacol：矢志方通过抑制NLRP3炎性体改善高尿酸血症肾小管上皮细胞焦亡, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=73dbe76977a2)], followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=2184530, encodeId=c89f218453048, content=基于<a href='/topic/show?id=ec9e9482383' target=_blank style='color:#2F92EE;'>#透明质酸#</a>（HA）<a href='/topic/show?id=65a2e7058ef' target=_blank style='color:#2F92EE;'>#紫杉醇#</a>（PTX）前药与免疫系统的“传令兵”<a href='/topic/show?id=9b3996e6940' target=_blank style='color:#2F92EE;'>#锰#</a>离子（Mn2+），设计了一种新型复合纳米粒（Mn-HSP）。Mn-HSP一方面可通过<a href='/topic/show?id=bd5be795632' target=_blank style='color:#2F92EE;'>#细胞焦亡#</a>暴露肿瘤“情报”，另一方面可通过“传令兵”Mn2+介导的<a href='/topic/show?id=574d11064646' target=_blank style='color:#2F92EE;'>#干扰素刺激基因#</a>（STING）通路打开<a href='/topic/show?id=aa0582e6946' target=_blank style='color:#2F92EE;'>#肿瘤#</a>防御缺口，协助“情报”传递并促进“攻击部队”向肿瘤渗透，进而明显抑制了肿瘤的复发及转移。, objectTitle=中国海洋大学赵峡教授团队Biomaterials：基于细胞焦亡和STING通路抗癌有点“锰”, objectType=article, longId=811351, objectId=a06181135191, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/Random/medical-conference-P42ZDP5.jpg, objectUrl=/article/show_article.do?id=a06181135191, replyNumber=0, likeNumber=111, createdTime=2024-01-29, rootId=0, userName=侠胆医心, userId=f63e4754896, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=加利福尼亚, moduleDTOList=[ModuleDTO(moduleId=a06181135191, moduleTitle=中国海洋大学赵峡教授团队Biomaterials：基于细胞焦亡和STING通路抗癌有点“锰”, moduleType=article, 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hrefUrl=https://www.medsci.cn/article/show_article.do?id=a06181135191)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2183082, encodeId=1aa02183082ec, content=<a href='/topic/show?id=384b8220449' target=_blank style='color:#2F92EE;'>#肺癌#</a> <a href='/topic/show?id=9efb80281aa' target=_blank style='color:#2F92EE;'>#老药新用#</a> <a href='/topic/show?id=bd5be795632' target=_blank style='color:#2F92EE;'>#细胞焦亡#</a> <a href='/topic/show?id=191711035234' target=_blank style='color:#2F92EE;'>#氯雷他定#</a> <a href='/topic/show?id=1419103924ce' target=_blank style='color:#2F92EE;'>#焦亡#</a>, objectTitle=JECCR：何建行/梁文华团队发现老牌抗过敏药氯雷他定可诱导肺癌细胞凋亡和焦亡！, objectType=article, longId=810437, objectId=9fc181043e36, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/images/20240118/467925c45c3247279f1be9a74cc89484.jpg, objectUrl=/article/show_article.do?id=9fc181043e36, replyNumber=0, likeNumber=158, createdTime=2024-01-22, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=加利福尼亚, moduleDTOList=[ModuleDTO(moduleId=9fc181043e36, moduleTitle=JECCR：何建行/梁文华团队发现老牌抗过敏药氯雷他定可诱导肺癌细胞凋亡和焦亡！, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=9fc181043e36)], followStatus=false, userIsMember=false, type=null, lengthMark=0)] 梅斯话题小助手

细胞焦亡

2020-05-29

梅斯管理员

#牙周炎# #昼夜节律紊乱# #细胞焦亡#

Int. J. Oral Sci.：昼夜节律紊乱通过调控BMAL1和GSDMD介导的细胞焦亡加重牙周炎

2025-03-02发表于陕西省

梅斯管理员

#重症急性胰腺炎# #NLRP3# #急性肺损伤# #MMP9# #细胞焦亡# #柴黄清腹丸#

J Inflamm Res：柴黄清腹丸通过MMP9-NLRP3-焦亡通路保护急性胰腺炎相关性急性肺损伤

2025-02-25发表于陕西省

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#内皮细胞# #糖尿病性视网膜病变# #细胞焦亡# #GSDMD# #原花青素B2#

J Ethnopharmacol：原花青素B2通过抑制caspase-1/GSDMD介导的焦亡来减轻糖尿病视网膜病变的微血管功能障碍

2025-02-24发表于陕西省

梅斯管理员

#阿尔茨海默病# #自噬# #细胞焦亡# #郁金# #PINK1/Parkin通路#

Phytomedicine：郁金提取物通过PINK1/Parkin介导的自噬减轻阿尔茨海默病的认知缺陷，抑制焦亡

2025-02-17发表于陕西省

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#抑郁症# #P2X7# #柴胡# #柴胡皂苷# #细胞焦亡# #N9#

Phytomedicine：柴胡皂苷通过结合抑制P2X7表达缓解抑郁症的小胶质细胞焦亡

2024-12-08发表于陕西省

梅斯管理员

#肺动脉高压# #血管重塑# #细胞焦亡# #Cathepsin L# #组织蛋白酶L#

Hypertension：陈丰原、卜军团队和李晓晖团队揭示Cathepsin L促进肺动脉高压的作用机制

2024-11-03发表于威斯康星

梅斯管理员

#自噬# #黄芪# #当归# #细胞焦亡# #脑缺血/再灌注损伤# #AMPK/mTOR通路#

J Ethnopharmacol：黄芪-当归药对通过AMPK/mTOR信号通路促进大鼠大脑中动脉闭塞/再灌注后的自噬活性减轻焦亡

2024-10-29发表于上海

梅斯管理员

#LPS# #NLRP3# #细胞焦亡# #子宫内膜炎# #妇科千金胶囊#

J Ethnopharmacol：妇科千金胶囊通过调节TLR4/ NF-κB /NLRP3通路抑制炎症和焦亡，减轻子宫内膜炎

2024-10-25发表于上海

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#肺动脉高压# #细胞焦亡# #组织蛋白酶 L #

Hypertension：组织蛋白酶 L 通过 BMPR2/GSDME 介导的细胞焦亡促进肺动脉高压

2024-10-18发表于上海

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2024-09-13发表于上海

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2024-09-10发表于上海

梅斯管理员

#免疫治疗# #牙周炎# #细胞焦亡# #双金属有机框架#

吉林大学李春艳教授NSR：ATP 响应性的金属有机框架通过离子干扰抑制细胞焦亡治疗牙周炎

2024-08-14发表于上海

梅斯管理员

#细胞焦亡# #铜死亡#

Cell Metabolism：王晓东团队铜死亡最新研究，发现新型铜离子转运蛋白，并揭示其在铜死亡中的关键作用

2024-08-14发表于威斯康星

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#实体瘤# #蛋白酶体抑制剂# #细胞焦亡# #有丝分裂突变#

STTT：中山大学庄诗美团队通过抑制蛋白酶体和WEE家族激酶协同诱导有丝分裂焦亡和肿瘤缓解

2024-07-15发表于上海

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2024-05-08发表于上海

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#肿瘤微环境# #细胞焦亡# #铜死亡#

南洋理工大学赵彦利ACS Nano：MOF基纳米疫苗通过抑制巨噬细胞胞葬和促进癌细胞焦亡/铜死亡来缓解免疫抑制性肿瘤

2024-05-07发表于上海

侠胆医心

#高尿酸血症#(HUA)诱导的肾小管上皮细胞焦亡是肾小管损伤的重要原因。中药复方矢志方(SZF)由#王不留行#、#车前子#、#白芥子#、#冬葵子#组成，可活血通络、化痰祛湿，能改善#尿酸#(UA)诱导的肾小管#细胞焦亡#。

J Ethnopharmacol：矢志方通过抑制NLRP3炎性体改善高尿酸血症肾小管上皮细胞焦亡

2024-01-29发表于加利福尼亚

侠胆医心

全文收起基于#透明质酸#（HA）#紫杉醇#（PTX）前药与免疫系统的“传令兵”#锰#离子（Mn2+），设计了一种新型复合纳米粒（Mn-HSP）。Mn-HSP一方面可通过#细胞焦亡#暴露肿瘤“情报”，另一方面可通过“传令兵”Mn2+介导的#干扰素刺激基因#（STING）通路打开#肿瘤#防御缺口，协助“情报”传递并促进“攻击部队”向肿瘤渗透，进而明显抑制了肿瘤的复发及转移。

中国海洋大学赵峡教授团队Biomaterials：基于细胞焦亡和STING通路抗癌有点“锰”

2024-01-29发表于加利福尼亚

梅斯管理员

#细胞焦亡# #STING通路#

中国海洋大学赵峡教授团队Biomaterials：基于细胞焦亡和STING通路抗癌有点“锰”

2024-01-29发表于陕西省

梅斯管理员

#肺癌# #老药新用# #细胞焦亡# #氯雷他定# #焦亡#

JECCR：何建行/梁文华团队发现老牌抗过敏药氯雷他定可诱导肺癌细胞凋亡和焦亡！

2024-01-22发表于加利福尼亚

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