HSP90 inhibition overcomes EGFR amplification-induced resistance to third-generation EGFR-TKIs

Watanabe, S; Goto, Y; Yasuda, H; Kohno, T; Motoi, N; Ohe, Y; Nishikawa, H; Kobayashi, SS; Kuwano, K; Togashi, Y

Goto, Y (corresponding author), Natl Canc Ctr, Dept Thorac Oncol, Chuo Ku, 1-1,Tsukiji 5, Tokyo 1040045, Japan.; Togashi, Y (corresponding author), Natl Canc Ctr, Res Inst, Exploratory Oncol Res & Clin Trial Ctr EPOC, Div Canc Immunol, Tokyo 1040045, Japan.

THORACIC CANCER, 2021; 12 (5): 631

Abstract

Background: Patients with non-small cell lung cancer (NSCLC) harboring activating EGFR mutations are sensitive to epidermal growth factor receptor-tyr......

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