Allosteric Methods and Their Applications: Facilitating the Discovery of Allosteric Drugs and the Investigation of Allosteric Mechanisms

Lu, SY; Shen, QC; Zhang, J

Zhang, J (reprint author), Shanghai Jiao Tong Univ, Sch Med, Chinese Minist Educ, Dept Pathophysiol,Key Lab Cell Differentiat & Apo, Shanghai 200025, Peoples R China.; Zhang, J (reprint author), Shanghai Jiao Tong Univ, Sch Med, Med Bioinformat Ctr, Shang

ACCOUNTS OF CHEMICAL RESEARCH, 2019; 52 (2): 492

Abstract

CONSPECTUS: Allostery, or allosteric regulation, is the phenomenon in which protein functional activity is altered by the binding of an effector at an......

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