Panax notoginseng Saponins Attenuate Neuroinflammation through TXNIP-Mediated NLRP3 Inflammasome Activation in Aging Rats

Zhou, ZY; He, MH; Zhao, QQ; Wang, DF; Zhang, CC; Liu, CQ; Zhao, HX; Dun, YY; He, YM; Yuan, CF; Yuan, D; Wang, T

Yuan, D (corresponding author), China Three Gorges Univ, Med Coll, 8 Univ Rd, Yichang 443002, Hubei, Peoples R China.; Wang, T (corresponding author), Wuhan Univ Sci & Technol, Pharm Dept, 1 Huangjiahu Univ Town, Wuhan 430065, Hubei, Peoples R China.

CURRENT PHARMACEUTICAL BIOTECHNOLOGY, 2021; 22 (10): 1369

Abstract

Introduction: Microglia-mediated inflammatory responses play a crucial role in aging-related neurodegenerative diseases. The TXNIP/NLRP3 pathway is a ......

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