Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis

Chinta, KC; Rahman, MA; Saini, V; Glasgow, JN; Reddy, VP; Lever, JM; Nhamoyebonde, S; Leslie, A; Wells, RM; Traylor, A; Madansein, R; Siegal, GP; Antony, VB; Deshane, J; Wells, G; Nargan, K; George, JF; Ramdial, PK; Agarwal, A; Steyn, AJC

Steyn, AJC (reprint author), Univ Alabama Birmingham, Sch Med, Dept Microbiol, Birmingham, AL 35294 USA.; Steyn, AJC (reprint author), Africa Hlth Res Inst, ZA-4001 Durban, South Africa.; Steyn, AJC (reprint author), Univ Alabama Birmingham, UAB Ctr AIDS

CELL REPORTS, 2018; 25 (7): 1938

Abstract

Heme oxygenase-1 (HO-1) is a cytoprotective enzyme that controls inflammatory responses and redox homeostasis; however, its role during pulmonary tube......

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