The microanatomic segregation of selection by apoptosis in the germinal center

Mayer, CT; Gazumyan, A; Kara, EE; Gitlin, AD; Golijanin, J; Viant, C; Pai, J; Oliveira, TY; Wang, Q; Escolano, A; Medina-Ramirez, M; Sanders, RW; Nussenzweig, MC

Nussenzweig, MC (reprint author), Rockefeller Univ, Lab Mol Immunol, New York, NY 10065 USA.; Nussenzweig, MC (reprint author), Rockefeller Univ, HHMI, New York, NY 10065 USA.

SCIENCE, 2017; 358 (6360):

Abstract

B cells undergo rapid cell division and affinity maturation in anatomically distinct sites in lymphoid organs called germinal centers (GCs). Homeostas......

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