Kinase-independent synthesis of 3-phosphorylated phosphoinositides by a phosphotransferase

Walpole, GFW; Pacheco, J; Chauhan, N; Clark, J; Anderson, KE; Abbas, YM; Brabant-Kirwan, D; Montano-Rendon, F; Liu, ZT; Zhu, HX; Brumell, JH; Deiters, A; Stephens, LR; Hawkins, PT; Hammond, GRV; Grinstein, S; Fairn, GD

Grinstein, S (通讯作者)，Hosp Sick Children, Div Cell Biol, Toronto, ON, Canada.;Grinstein, S; Fairn, GD (通讯作者)，Univ Toronto, Dept Biochem, Toronto, ON, Canada.;Grinstein, S; Fairn, GD (通讯作者)，St Michaels Hosp, Keenan Res Ctr Biomed Sci, Toronto, ON, Canada.;Grinstein, S; Fairn, GD (通讯作者)，Univ Toronto, Inst Med Sci, Toronto, ON, Canada.;Fairn, GD (通讯作者)，Dalhousie Univ, Dept Pathol, Halifax, NS, Canada.

NATURE CELL BIOLOGY, 2022; 24 (5): 708

Abstract

Despite their low abundance, phosphoinositides play a central role in membrane traffic and signalling. PtdIns(3,4,5)P-3 and PtdIns(3,4)P-2 are uniquel......

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