MNK2 deficiency potentiates beta-cell regeneration via translational regulation

Karampelias, C; Watt, K; Mattsson, CL; Ruiz, AF; Rezanejad, H; Mi, JR; Liu, XJ; Chu, LH; Locasale, JW; Korbutt, GS; Rovira, M; Larsson, O; Andersson, O

Andersson, O (通讯作者)，Karolinska Inst, Dept Cell & Mol Biol, Stockholm, Sweden.

NATURE CHEMICAL BIOLOGY, 2022; 18 (9): 942

Abstract

Regenerating pancreatic beta-cells is a potential curative approach for diabetes. We previously identified the small molecule CID661578 as a potent in......

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