Nuclear localisation of Aurora-A: its regulation and significance for Aurora-A functions in cancer

Naso, FD; Boi, D; Ascanelli, C; Pamfil, G; Lindon, C; Paiardini, A; Guarguaglini, G

Guarguaglini, G (corresponding author), Sapienza Univ Rome, Inst Mol Biol & Pathol, Natl Res Council Italy, Rome, Italy.; Paiardini, A (corresponding author), Sapienza Univ Rome, Dept Biochem Sci, Rome, Italy.; Lindon, C (corresponding author), Univ Cambridge, Dept Pharmacol, Cambridge, England.

ONCOGENE, 2021; 40 (23): 3917

Abstract

The Aurora-A kinase regulates cell division, by controlling centrosome biology and spindle assembly. Cancer cells often display elevated levels of the......

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