Enantioselective Total Synthesis of (-)-Finerenone Using Asymmetric Transfer Hydrogenation

Lerchen, A; Gandhamsetty, N; Farrar, EHE; Winter, N; Platzek, J; Grayson, MN; Aggarwal, VK

Aggarwal, VK (corresponding author), Univ Bristol, Sch Chem, Bristol BS8 1TS, Avon, England.; Grayson, MN (corresponding author), Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020; 59 (51): 23107

Abstract

(-)-Finerenone is a nonsteroidal mineralocorticoid receptor antagonist currently in phase III clinical trials for the treatment of chronic kidney dise......

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