METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation

Pandolfini, L; Barbieri, I; Bannister, AJ; Hendrick, A; Andrews, B; Webster, N; Murat, P; Mach, P; Brandi, R; Robson, SC; Migliori, V; Alendar, A; d'Onofrio, M; Balasubramanian, S; Kouzarides, T

Kouzarides, T (reprint author), Univ Cambridge, Gurdon Inst, Tennis Court Rd, Cambridge CB2 1QN, England.; Kouzarides, T (reprint author), Univ Cambridge, Dept Pathol, Tennis Court Rd, Cambridge CB2 1QN, England.

MOLECULAR CELL, 2019; 74 (6): 1278

Abstract

7-methylguanosine (m7G) is present at mRNA caps and at defined internal positions within tRNAs and rRNAs. However, its detection within low-abundance ......

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