Small-Molecule Inhibitors of the m7G-RNA Writer METTL1

Nai, F; Espinoza, MPF; Invernizzi, A; Vargas-Rosales, PA; Bobileva, O; Herok, M; Caflisch, A

Caflisch, A (通讯作者)，Univ Zurich, Dept Biochem, CH-8057 Zurich, Switzerland.

ACS BIO & MED CHEM AU, 2023; ():

Abstract

We discovered the first inhibitors of the m7G-RNA writer METTL1 by high-throughput docking and an enzymatic assay based on luminescence. Eleven compou......

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