TGF-beta 1-induced cell migration in pancreatic carcinoma cells is RAC1 and NOX4-dependent and requires RAC1 and NOX4-dependent activation of p38 MAPK

Witte, D; Bartscht, T; Kaufmann, R; Pries, R; Settmacher, U; Lehnert, H; Ungefroren, H

Ungefroren, H (reprint author), Univ Hosp Schleswig Holstein, Dept Med 1, Campus Lubeck, D-23538 Lubeck, Germany.; Ungefroren, H (reprint author), Univ Lubeck, Ratzeburger Allee 160, D-23538 Lubeck, Germany.

ONCOLOGY REPORTS, 2017; 38 (6): 3693

Abstract

Transforming growth factor (TGF)-beta promotes epithelial-mesenchymal transition and cell invasion of cancer cells in part through the small GTPase RA......

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