Fortilin interacts with TGF-beta 1 and prevents TGF-beta receptor activation

Pinkaew, D; Martinez-Hackert, E; Jia, W; King, MD; Miao, F; Enger, NR; Silakit, R; Ramana, K; Chen, SY; Fujise, K

Fujise, K (通讯作者)，Univ Washington, Div Cardiol, Dept Med, Seattle, WA 98109 USA.

COMMUNICATIONS BIOLOGY, 2022; 5 (1):

Abstract

Fortilin prevents the activation of the TGF-beta 1 receptor by occupying the pocket of TGF-beta 1 and competing with TGF-beta RII to bind with TGF-bet......

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