KCC2 downregulation facilitates epileptic seizures

Chen, LL; Wan, L; Wu, Z; Ren, WT; Huang, YA; Qian, BB; Wang, Y

Wang, Y (reprint author), Fudan Univ, Inst Brain Sci, State Key Lab Med Neurobiol, Collaborat Innovat Ctr Brain Sci, Shanghai 200032, Peoples R China.

SCIENTIFIC REPORTS, 2017; 7 ( ):

Abstract

GABA(A) receptor-mediated inhibition depends on the maintenance of low level intracellular [Cl-] concentration, which in adult depends on neuron speci......

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