Enhancing KCC2 function counteracts morphine-induced hyperalgesia

Ferrini, F; Lorenzo, LE; Godin, AG; Le Quang, M; De Koninck, Y

De Koninck, Y (reprint author), Inst Univ Sante Mentale Quebec, CERVO Brain Res Ctr, Quebec City, PQ, Canada.; De Koninck, Y (reprint author), Univ Laval, Dept Psychiat & Neurosci, Quebec City, PQ, Canada.

SCIENTIFIC REPORTS, 2017; 7 ( ):

Abstract

Morphine-induced hyperalgesia (MIH) is a severe adverse effect accompanying repeated morphine treatment, causing a paradoxical decrease in nociceptive......

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