Accelerated Blood Clearance of Nanoemulsions Modified with PEG-Cholesterol and PEG-Phospholipid Derivatives in Rats: The Effect of PEG-Lipid Linkages and PEG Molecular Weights

Liu, MY; Chu, YY; Liu, H; Su, YQ; Zhang, Q; Jiao, J; Liu, MQ; Ding, JQ; Liu, M; Hu, YW; Dai, YY; Zhang, RP; Liu, XR; Deng, YH; Song, YZ

Deng, YH; Song, YZ (corresponding author), Shenyang Pharmaceut Univ, Coll Pharm, Shenyang 110016, Liaoning, Peoples R China.

MOLECULAR PHARMACEUTICS, 2020; 17 (4): 1059

Abstract

Various types of nanocarriers modified with poly(ethylene glycol) (PEG) exhibit the accelerated blood clearance (ABC) phenomenon, resulting in reduced......

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