ADAM17 stabilizes its interacting partner inactive Rhomboid 2 (iRhom2) but not inactive Rhomboid 1 (iRhom1)

Weskamp, G; Tushaus, J; Li, D; Feederle, R; Maretzky, T; Swendemann, S; Falck-Pedersen, E; McIlwain, DR; Mak, TW; Salmon, JE; Lichtenthaler, SF; Blobel, CP

Blobel, CP (corresponding author), Hosp Special Surg, Weill Cornell Med, Arthrit & Tissue Degenerat Program, 535 E 70th St, New York, NY 10021 USA.

JOURNAL OF BIOLOGICAL CHEMISTRY, 2020; 295 (13): 4350

Abstract

The metalloprotease ADAM17 (a disintegrin and metalloprotease 17) is a key regulator of tumor necrosis factor ? (TNF?), interleukin 6 receptor (IL-6R)......

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