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At the dawn of this century, which many believe would be the most technologically far-reaching in the history of this planet, the discipline of computer modeling, which lies at the intersection of the bio-info-nano technologies, is poised to bring about revolutionary changes in our lives, in our society, and the world we live in. Computer Modeling will be the core enabling-discipline for all technological & scientific advances that are yet to be made in this century. It involves a diverse set of research thrusts, in several focus areas, as for instance: CMES "FOCUS DISCIPLINES": a) Contemporary Engineering, Physical, Chemical & Biological Sciences; b) Systems Integration through Computations; and c) Advanced Communications and Information Processing Technologies.