The Journal of Nephrology considers the publication of peer-reviewed original manuscripts dealing with both clinical and laboratory investigations of relevance to the broad fields of nephrology, dialysis and transplantation. Submission of research manuscripts covering diverse topics and problems (Original Investigations) is encouraged. However, comprehensive reviews on relevant topics (Reviews), reports of clinical cases of special interest (Case Reports), and brief reports on the protocols of new ongoing trials (Research Protocols) will also be considered. Finally, the submission of articles on technical or methodological aspects of research (Methods and Procedures), which can be more exhaustively and accurately documented through the multimedia facilities offered by the JNonline (the WEB edition of the journal), is also encouraged.