Clinical and Vaccine Immunology (CVI) is an expansion of the former Clinical and Diagnostic Laboratory Immunology. CVI publishes articles on topics related to clinical immunology and vaccine research. The CVI scope includes research studies that enhance understanding of the human immune response in health and disease, including new animal models for human immunologic diseases, and viral immunology and immunopathogenesis. The journal particularly welcomes articles on all aspects of immunization and vaccine research, including development and evaluation of vaccines, the immune response to vaccines in humans and animals, studies of vaccine vectors, adjuvants and immunomodulators, quantitative assays of vaccine efficacy, and clinical trial studies. Medical and veterinary laboratory immunology continues to be a focus of the journal.