2025 ASON立场声明:免疫检查点抑制剂相关肾毒性的诊断和管理

2025-01-02 Kidney Int 发表于上海

本文主要针对ICI-AKI的初步评估和诊断、管理和免疫抑制治疗以及AKI发作后ICI再挑战的考虑提供临床实践要点。

中文标题:

2025 ASON立场声明:免疫检查点抑制剂相关肾毒性的诊断和管理

英文标题:

Diagnosis and management of immune checkpoint inhibitor-associated nephrotoxicity: a position statement from the American Society of Onco-nephrology

发布机构:

发布日期:

2025-01-02

简要介绍:

免疫检查点抑制剂(ICIs)已改变癌症的治疗,现在是几种恶性肿瘤治疗的支柱。但ICIs可引起一系列肾脏免疫相关不良事件,包括急性肾损伤(AKI),最常见的表现为急性间质性肾炎(AIN)。本文主要针对ICI-AKI的初步评估和诊断、管理和免疫抑制治疗以及AKI发作后ICI再挑战的考虑提供临床实践要点。

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