Diabetes Obes Metab:警告!许多2型糖尿病患者存在过度治疗,这样做更危险

2018-01-24 Heather_z727 来宝网

糖尿病已经成为影响全球健康最大的隐患之一,据不完全统计,全球范围内,糖尿病的人数呈不断上涨的趋势。其中,2型糖尿病尤为严重。年龄是2型糖尿病的一个风险因素,因此,在2型糖尿病患者中,老年患者占据了大多数。在最近的一次糖尿病、肥胖和代谢分析中,70岁的2型糖尿病患者有将近40%显示过度治疗。

许多老年2型糖尿病患者过度治疗糖尿病已经成为影响全球健康最大的隐患之一,据不完全统计,全球范围内,糖尿病的人数呈不断上涨的趋势。其中,2型糖尿病尤为严重。年龄是2型糖尿病的一个风险因素,因此,在2型糖尿病患者中,老年患者占据了大多数。在最近的一次糖尿病、肥胖和代谢分析中,70岁的2型糖尿病患者有将近40%显示过度治疗。

众所周知,对于糖尿病患者来说,血糖的控制是最为重要的。一旦血糖控制不当,将会带来各种严重的并发症。然而,人们可能很少考虑过度治疗带来的副作用。在此次研究过程中,研究人员发现,大多数过度治疗的人身体虚弱,他们使用了5种降低血糖的药物。其中20.3%的糖尿病患者发生低血糖,近30%人出现过跌倒事故。低血糖是降糖药物或糖尿病治疗带来的最可怕的副作用之一,有时,糖尿病患者很可能会因此失去生命,因此,研究人员提醒广大临床医生,在保留“一刀切”治疗方法的同时,应该认识到个性化治疗可能带来的好处。

来自荷兰乌得勒支大学医学中心的研究人员表示:“对于长期患有糖尿病的老年患者需要详细的治疗方案,严格控制血糖治疗的风险。”

“医生们要遵守指导方针,根据老年糖尿病患者的具体情况,适当减少降糖药物的使用。”

原始出处:

Huberta E. Hart et al. Overtreatment of older patients with type 2 diabetes mellitus in primary care. Diabetes, Obesity and Metabolism (2017). DOI: 10.1111/dom.13174

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createdBy=0045169, createdName=木头人513, createdTime=Fri Mar 23 03:41:00 CST 2018, time=2018-03-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1745094, encodeId=f46e1e45094bc, content=<a href='/topic/show?id=321a940118c' target=_blank style='color:#2F92EE;'>#过度治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94011, encryptionId=321a940118c, topicName=过度治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6e6435510490, createdName=jxrzshh, createdTime=Sat Jul 28 17:41:00 CST 2018, time=2018-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1896250, encodeId=15c618962503b, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, 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CST 2018, time=2018-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474410, encodeId=80f614e4410e5, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Fri Jan 26 14:41:00 CST 2018, time=2018-01-26, status=1, ipAttribution=)]
    2018-10-09 一闲
  5. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Sat Dec 01 12:41:00 CST 2018, time=2018-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=283858, encodeId=f8162838587c, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Wed Jan 31 14:35:17 CST 2018, time=2018-01-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=282724, 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CST 2018, time=2018-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474410, encodeId=80f614e4410e5, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Fri Jan 26 14:41:00 CST 2018, time=2018-01-26, status=1, ipAttribution=)]
  6. 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encodeId=e9d1282e24e3, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Sun Jan 28 00:50:13 CST 2018, time=2018-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1383396, encodeId=22d21383396ec, content=<a href='/topic/show?id=196a1101f7' target=_blank style='color:#2F92EE;'>#2型糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1101, encryptionId=196a1101f7, topicName=2型糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=智者为医08, createdTime=Fri Jan 26 14:41:00 CST 2018, time=2018-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474410, encodeId=80f614e4410e5, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Fri Jan 26 14:41:00 CST 2018, time=2018-01-26, status=1, ipAttribution=)]
    2018-12-01 仁者大医
  7. 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    2018-01-31 jihuaijun1112

    学习学习学习

    0

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    2018-01-28 jihuaijun1112

    学习学习学习

    0

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加州大学旧金山分校的研究人员在脂肪细胞中发现了一种新的生物途径,这可以解释为什么一些肥胖的人患2型糖尿病等代谢疾病的风险很高。这项新发现最初在小鼠身上得到了人类患者数据的支持,可能会带来新的生物标记物来预测谁处于危险之中,并指导治疗以减轻肥胖带来的医疗负担。

新方向|基层糖尿病分级诊疗“启明灯”

基于我国糖尿病管理现状和国家推行分级诊疗的政策背景,在国家卫生计生委指导下,白求恩公益基金会与中华医学会糖尿病学分会CDS联合,共同开展了中国基层糖尿病分级诊疗模式的探索与评价项目,即路标研究(“ROADMAP研究”)。

Diabetes Care:糖尿病对乳腺癌治疗和预后的影响!

由此可见,尽管患有糖尿病和不伴有糖尿病患者接受癌症治疗相似,但在糖尿病病程较长或已有心血管疾病的妇女中乳腺癌特异性死亡率仍然较高。这项研究揭示了糖尿病和乳腺癌患者预后不良的主要危险因素的新信息。

JAMA:胃旁路术、生活方式干预联合药物治疗可改善肥胖II型糖尿病患者多种生化指标

研究认为,对于肥胖的II型糖尿病患者,接受胃旁路术,较单纯的药物和生活方式干预可更有效的控制多种代谢指标,更进一步的长期随访有待进行

JAMA Intern Med:30年随访证实6个月以上母乳喂养即可大幅降低母亲糖尿病风险

研究通过纵向生化证据证实,母乳喂养可大大降低母亲的糖尿病风险,持续6个月以上的母乳喂养即可获得最大的糖尿病风险降低收益

Hypertension:当高血压遇上糖尿病!

很多人会同时患有2型糖尿病和高血压。在多种学科中,糖尿病的发展主要表现为血浆葡萄糖水平相对快速增长。但目前尚不知道在高血压的发展过程中是否存在相似的现象。现有研究人员利用随访了7年MCDS和FOS研究中的数据对有无糖尿病的患者的高血压发展过程中血压(BP)变化模式进行分析。糖尿病基础水平是高血压发病的重要预测指标(FOS,优势比 3.14;95% CI 2.17-4.54),且独立于性别、年龄、体