Hypertension:当高血压遇上糖尿病!

2018-01-18 MedSci MedSci原创

很多人会同时患有2型糖尿病和高血压。在多种学科中,糖尿病的发展主要表现为血浆葡萄糖水平相对快速增长。但目前尚不知道在高血压的发展过程中是否存在相似的现象。现有研究人员利用随访了7年MCDS和FOS研究中的数据对有无糖尿病的患者的高血压发展过程中血压(BP)变化模式进行分析。糖尿病基础水平是高血压发病的重要预测指标(FOS,优势比 3.14;95% CI 2.17-4.54),且独立于性别、年龄、体

很多人会同时患有2型糖尿病高血压。在多种学科中,糖尿病的发展主要表现为血浆葡萄糖水平相对快速增长。但目前尚不知道在高血压的发展过程中是否存在相似的现象。

现有研究人员利用随访了7年MCDS和FOS研究中的数据对有无糖尿病的患者的高血压发展过程中血压(BP)变化模式进行分析。糖尿病基础水平是高血压发病的重要预测指标(FOS,优势比 3.14;95% CI 2.17-4.54),且独立于性别、年龄、体重指数和家族糖尿病史之外。相反的,基础高血压是糖尿病发病的非独立预测指标(FOS,优势比 3.33;95% CI 2.50-4.44)。在60%以上的转变中,从正常血压到高血压进展的特征是血压急剧升高,3年半内收缩压平均升高20mmHg(MCDS研究)。与未变化的群体相比,高血压和糖尿病变化有相同的代谢综合征表型(高胰岛素血症,体重指数、腰围、BP、心率和脉搏压均升高,以及血脂异常)。

总而言之,两种疾病人群中的结果相似。随着时间的推移,高血压和糖尿病的发展相互联系;血压升高的特点是急剧升高;胰岛素抵抗是糖尿病前期和高血压前期共同特点,也是疾病进展到两种疾病状态的前提。

原始出处:

Vasilis Tsimihodimos, et al.Hypertension and Diabetes Mellitus.Hypertension. January 15,2018. https://doi.org/10.1161/HYPERTENSIONAHA.117.10546

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    2018-06-20 feather89
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    2018-01-19 飛歌

    学习了很有用

    0

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    2018-01-18 1e1b8538m79(暂无匿称)

    不错的文章不错的文章

    0

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    2018-01-18 131****2916

    不错的文章.值得推荐

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