血液标志物用于临床肝细胞癌早期筛查的专家共识

2021-09-20 中华预防医学会感染性疾病防控分会 中国病毒病杂志

我国原发性肝癌(肝癌)疾病负担严重,预后不理想。通过简便的方法对肝癌高危人群进行早期筛查,是实现早期诊断和早期治疗,提高肝癌生存率的关键。

中文标题:

血液标志物用于临床肝细胞癌早期筛查的专家共识

发布日期:

2021-09-20

简要介绍:

我国原发性肝癌(肝癌)疾病负担严重,预后不理想。通过简便的方法对肝癌高危人群进行早期筛查,是实现早期诊断和早期治疗,提高肝癌生存率的关键。目前在肝癌的早期筛查方面,甲胎蛋白(alpha fetoprotein, AFP)等血液学检查仍是主要手段,但是其灵敏度及特异度有限,存在高漏诊风险。近年来随着科学技术的不断发展,对传统检测方法的改进以及新兴标志物如甲基化DNA、微小RNA等的出现,为进一步提高早期肝癌筛查的灵敏度和特异度带来了希望。此专家共识总结了传统及新型血液学检查手段的研究进展,并提出了在肝癌早期筛查中应用的专家指导意见,旨在为肝癌早期筛查中血液学检查的应用提供依据,改善我国肝癌防控水平。 

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