Biomed Res Int:苏州医工所在低剂量CT成像研究中取得进展

2017-04-29 李铭 苏州生物医学工程技术研究所

当前,随着CT断层扫描在医学诊断中的应用越来越广泛,CT成像中的低剂量成像问题已经引起了人们越来越多的关注。大量的临床实践表明超过正常范围的CT 辐射剂量与人体新陈代谢异常乃至癌症等疾病的诱发密切相关。然而,在目前的CT设备中,采用低剂量扫描协议采集到的影像会导致重建图像噪声和伪影严重,影响临床医生对异常组织的确诊率。低剂量成像协议主要包含:1)采用降采样曝光;2)采用较低的管压和管电流曝光。前者

当前,随着CT断层扫描在医学诊断中的应用越来越广泛,CT成像中的低剂量成像问题已经引起了人们越来越多的关注。大量的临床实践表明超过正常范围的CT 辐射剂量与人体新陈代谢异常乃至癌症等疾病的诱发密切相关。然而,在目前的CT设备中,采用低剂量扫描协议采集到的影像会导致重建图像噪声和伪影严重,影响临床医生对异常组织的确诊率。低剂量成像协议主要包含:1)采用降采样曝光;2)采用较低的管压和管电流曝光。前者更适用于开放式的CBCT设备,而后者更适用于螺旋CT设备。因此,如何利用低剂量协议采集的原始投影数据重建高质量的图像极具学术价值和临床价值。

苏州医工所医学影像室X射线组的李铭等人提出了基于SL0的正则化函数模型,该模型根据重建图像的噪声性质,自适应调整正则化约束强弱,从而取得较好的噪声抑制和软组织保护特性。该方法在仿真实验、临床数据实验及动物数据重建中均能取得较为理想的重建结果。

相关研究成果发表在SCI期刊BioMed Research International上,(Volume 2016, Article ID 2180457, 12 pages)。该成果得到了国家重点研发计划数字诊疗专项(批准号:2016YFC0103502,2016YFC0104505)、江苏省自然科学基金(BK20151232)等项目支持。

原始出处:

Li M, Zhang C, Peng C,et al.Smoothed l0 Norm Regularization for Sparse-View X-Ray CT Reconstruction.Biomed Res Int. 2016;2016:2180457. Epub 2016 Sep 20.

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    2017-05-20 sunylz
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    2017-04-29 1e1b142fm53(暂无匿称)

    学习了 谢谢

    0

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    2017-04-29 sy3923582

    学习了,谢谢

    0

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