Diabetic Med:Roux-en-Y胃旁路术和袖状胃切除术后对2型糖尿病的作用?

2018-07-04 MedSci MedSci原创

近日,国际杂志 《Diabetic Med》上在线发表一项关于Roux-en-Y胃旁路术和袖状胃切除术后2年缓解2型糖尿病-比较DiaRem和DiaBetter评分和减重的作用的研究。 Roux-en-Y胃绕道手术(RYGB)和袖状胃切除术对缓解2型糖尿病和体重减轻作用的比较疗效尚不清楚。本研究的目的是比较DiaRem和DiaBetter评分,包括糖尿病持续时间,在RYGB和袖状胃切除术后2

近日,国际杂志 《Diabetic Med》上在线发表一项关于Roux-en-Y胃旁路术和袖状胃切除术后2年缓解2糖尿病-比较DiaRemDiaBetter评分和减重的作用的研究。

Roux-en-Y胃绕道手术(RYGB)和袖状胃切除术对缓解2糖尿病和体重减轻作用的比较疗效尚不清楚。本研究的目的是比较DiaRemDiaBetter评分,包括糖尿病持续时间,在RYGB和袖状胃切除术后2年糖尿病缓解后,体重减轻和糖尿病缓解的相关性。

研究人员对进行RYGB107)或袖状胃切除术(103)和验证队列研究(173)的肥胖糖尿病患者进行了一项回顾性单中心队列研究。计算糖尿病缓解,体重减轻%,DiaRemDiaBetter评分和受试者特征(ROC)曲线下面积。使用逻辑回归来研究体重减轻%和糖尿病缓解之间的关系。

研究发现,DiaBetterDiaRem评分最低的患者获得糖尿病缓解的比例最高。ROC曲线下面积相当[DiaBetter0.86795CI0.817-0.916; DiaRem0.86595CI0.814-0.915),P = 0.856]RYGB术后2年体重下降百分比[26.695CI24.8-28.4]与袖状胃切除术后 [20.695CI18.3-22.8),P <0.001]相比更高。RYGB的糖尿病缓解率高达151[OR 2.5195CI1.12-5.60),P = 0.025]。当校正减重百分比时,这种关联变得不显著。

DiaBetterDiaRem评分可预测这两种手术的糖尿病缓解情况。两年的体重减轻在确定糖尿病缓解方面起着关键作用。

原始出处:

A. Pucci U. TymoszukW. H. Cheunget al. Type 2 diabetes remission 2 years post RouxenY gastric bypass and sleeve gastrectomy: the role of the weight loss and comparison of DiaRem and DiaBetter scores

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  5. 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  6. 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  7. 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  8. 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  9. 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    2018-07-06 bshuang
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近日,国际杂志 《Diabetologia》上在线发表一项关于Lp-PLA2在肥胖和2型糖尿病中的差异表达及脂质影响的研究。 脂蛋白相关磷脂酶A2(Lp-PLA2)是一种循环巨噬细胞衍生因子,随肥胖而增加,并导致心血管疾病(CVD)的风险增高。尽管如此,它在脂肪组织和脂肪细胞中的作用还不清楚。因此,本研究的目的是阐明Lp-PLA2在不同脂肪组织和2型糖尿病中的表达,并确定肥胖和2型糖尿病的标

JAHA:2型糖尿病患者服用二甲双胍与高血压风险之间的关系

由此可见,二甲双胍服用者发生高血压的风险降低,并且存在剂量效应关系。

Diabetic Med:2型糖尿病智力残疾成人的特征如何?

近日,国际杂志 《Diabetic Med》上在线发表一项关于2型糖尿病智力残疾成人表征的病例发现研究的结果。该报告是对有轻度至中度智力障碍2型糖尿病的成年人进行支持性自我管理干预的可行性试验期间,进行的病例研究结果,根据糖尿病控制、健康状况描述研究样本的特征,并寻找糖尿病管理服务和支持的方法。 研究人员在英国(2013年3月至2015年6月)进行了一项横截面病例调查研究,主要通过初级保健机

Diabetes Care:2型糖尿病患者收缩压降到多少为宜?

2018年6月,发表在《Diabetes Care》的一项由中国香港研究者进行的基于人群的回顾性队列研究,考察了收缩压(SBP)的实现对2型糖尿病(T2DM)患者心血管结局的影响。