BRCA-话题@MedSci

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BRCA

2020-05-29

智智灵药 (审核中...)

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#BRCA#

Lancet Oncology：3期SOLO1试验：奥拉帕利维持治疗显著改善了晚期卵巢癌伴BRCA突变铂类化疗后患者的无进展生存期

2021-05-23

智智灵药 (审核中...)

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#BRCA#

JCO：鲁卡帕利可有效治疗携带BRCA1/2或PALB2致病性突变的晚期胰腺癌

2021-05-14

智智灵药 (审核中...)

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#BRCA#

J Clin Oncol：注意！携带BRCA1致病性突变的女性或卵巢储备功能下降！

2021-04-28

智智灵药 (审核中...)

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#BRCA#

Cancer：BRCA1/2-、CDK12-和ATM-突变的转移去势抵抗性前列腺癌的差异化治疗结果

2021-03-28

智智灵药 (审核中...)

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#BRCA#

Eur J Cancer：激素替代治疗使45岁以上BRCA突变携带者乳腺癌风险增加3倍！

2021-03-25

智智灵药 (审核中...)

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#BRCA#

Clin Cancer Res：对3334名晚期前列腺癌患者的循环肿瘤DNA进行基因组学分析确定了可靶向的BRCA变异和AR耐药机制

2021-03-01

智智灵药 (审核中...)

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#BRCA#

Nat Commun：BRCA1/BRCA2突变携带者的乳腺癌发病风险研究

2021-02-24

智智灵药 (审核中...)

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#BRCA#

Br J Cancer：携带BRCA2突变的乳腺癌患者的生存率分析

2021-02-21

智智灵药 (审核中...)

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#BRCA#

BRCA1/2突变铂敏感型复发性卵巢癌：奥拉帕利较非铂化疗能有效改善PFS

2021-01-24

智智灵药 (审核中...)

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#BRCA#

NEJM双重磅：不仅是BRCA，乳腺癌风险与这些基因也密切相关！

2021-01-23

智智灵药 (审核中...)

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#BRCA#

Eur J Cancer：BRCA1/2突变对三阴性乳腺癌新辅助化疗时发生严重血液毒性风险的影响

2021-01-14

智智灵药 (审核中...)

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#BRCA#

ESMO Open：致病性BRCA1/2胚系突变在胰腺癌患者中的发生率

2021-01-10

智智灵药 (审核中...)

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#BRCA#

妇瘤探案 | 82岁/BRCAwt/心梗后，奥拉帕利维持治疗对高龄复发性卵巢癌患者有显效，PFS超22个月！

2020-12-15

智智灵药 (审核中...)

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#BRCA#

Clin Cancer Res：早期激素受体阳性乳腺癌患者的BRCAness和肿瘤炎症基因表达特征

2020-10-06

智智灵药 (审核中...)

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#BRCA#

Br J Cancer：ER表达状态对BRCA2突变型乳腺癌预后的影响

2020-09-23

智智灵药 (审核中...)

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#BRCA#

Lancet oncol：PARP抑制剂veliparib联合卡铂-紫杉醇治疗BRCA突变的晚期乳腺癌的疗效

2020-08-30

智智灵药 (审核中...)

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#BRCA#

Lancet oncol：奥拉帕利联合Durvalumab治疗BRCA突变的转移性乳腺癌

2020-08-12

智智灵药 (审核中...)

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#BRCA#

Eur J Cancer：HOXA9 meth-ctDNA可作为BRCA突变卵巢癌的生物标志物

2020-07-10

智智灵药 (审核中...)

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#BRCA#

Eur Urol：BRCA2基因组区域的前列腺癌风险评估

2020-07-10

智智灵药 (审核中...)

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#BRCA#

姚书忠教授：PARP抑制剂一线维持治疗生物标志物从BRCA+到HRD+，HRD Score检测助力卵巢癌获益人群筛查

2020-06-21

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