Inhibition of BCR signaling using the Syk inhibitor TAK-659 prevents stroma-mediated signaling in chronic lymphocytic leukemia cells

Purroy, N; Carabia, J; Abrisqueta, P; Egia, L; Aguilo, M; Carpio, C; Palacio, C; Crespo, M; Bosch, F

Crespo, M (reprint author), Univ Autonoma Barcelona, Vall Hebron Univ Hosp, Dept Hematol, Lab Expt Hematol, Barcelona, Spain.

ONCOTARGET, 2017; 8 (1): 742

Abstract

Proliferation and survival of chronic lymphocytic leukemia (CLL) cells depend on microenvironmental signals coming from lymphoid organs. One of the ke......

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