Water-soluble derivatives of evodiamine: Discovery of evodiamine-10-phosphate as an orally active antitumor lead compound

Chen, SQ; Bi, KJ; Wu, SC; Li, Y; Huang, YH; Sheng, CQ; Dong, GQ

Sheng, CQ; Dong, GQ (corresponding author), Second Mil Med Univ, Sch Pharm, Dept Med Chem, 325 Guohe Rd, Shanghai 200433, Peoples R China.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021; 220 ():

Abstract

10-Hydroxyevodiamine is a multitargeting antitumor lead compound with excellent in vitro activity. However, its in vivo antitumor potency is rather li......

Full Text Link