The small-molecule kinase inhibitor ceritinib, unlike imatinib, causes a significant disturbance of lipid membrane integrity: A combined experimental and MD study

Fischer, M; Luck, M; Werle, M; Vogel, A; Bashawat, M; Ludwig, K; Scheidt, HA; Müller, P

Scheidt, HA (通讯作者),Univ Leipzig, Inst Med Phys & Biophys, Hartelstr 16-18, D-04107 Leipzig, Germany.;Müller, P (通讯作者),Humboldt Univ, Dept Biol, Invalidenstr 42, D-10115 Berlin, Germany.

CHEMISTRY AND PHYSICS OF LIPIDS, 2023; 257 ():

Abstract

Ceritinib and imatinib are small-molecule protein kinase inhibitors which are applied as therapeutic agents against various diseases. The fundamentals......

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