Single-cell Analysis of CAR-T Cell Activation Reveals A Mixed T(H)1/T(H)2 Response Independent of Differentiation

Xhangolli, I; Dura, B; Lee, G; Kim, D; Xiao, Y; Fan, R

Fan, R (reprint author), Yale Univ, Dept Biomed Engn, New Haven, CT 06520 USA.; Fan, R (reprint author), Yale Canc Ctr, Yale Sch Med, New Haven, CT 06520 USA.; Fan, R (reprint author), Yale Stem Cell Ctr, Yale Sch Med, New Haven, CT 06520 USA.

GENOMICS PROTEOMICS & BIOINFORMATICS, 2019; 17 (2): 129

Abstract

The activation mechanism of chimeric antigen receptor (CAR)-engineered T cells may differ substantially from T cells carrying native T cell receptor, ......

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