CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondria! Fragmentation in Obesity

Hammerschmidt, P; Ostkotte, D; Nolte, H; Gerl, MJ; Jais, A; Brunner, HL; Sprenger, HG; Awazawa, M; Nicholls, HT; Turpin-Nolan, SM; Langer, T; Kruger, M; Brugger, B; Bruning, JC

Bruning, JC (reprint author), Max Planck Inst Metab Res, Dept Neuronal Control Metab, Gleueler Str 50, D-50931 Cologne, Germany.; Bruning, JC (reprint author), Univ Hosp Cologne, Ctr Endocrinol Diabet & Prevent Med CEDP, Kerpener Str 26, D-50924 Cologne,

CELL, 2019; 177 (6): 1536

Abstract

Ectopic lipid deposition and altered mitochondria! dynamics contribute to the development of obesity and insulin resistance. However, the mechanistic ......

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