Synthesis of tetrahydroisoquinolines through TiCl4-mediated cyclization and Et3SiH reduction

Shi, ZY; Xiao, Q; Yin, DL

Xiao, Q (corresponding author), Peking Union Med Coll & Chinese Acad Med Sci, State Key Lab Bioact Subst & Funct Nat Med, Inst Mat Med, Beijing 100050, Peoples R China.

CHINESE CHEMICAL LETTERS, 2020; 31 (3): 729

Abstract

A versatile and efficient telescoped reaction sequence for the synthesis of tetrahydroisoquinolines (THIQs) is reported that uses TiCl4 to promote cyc......

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