An Emerin LEM-Domain Mutation Impairs Cell Response to Mechanical Stress

Essawy, N; Samson, C; Petitalot, A; Moog, S; Bigot, A; Herrada, I; Marcelot, A; Arteni, AA; Coirault, C; Zinn-Justin, S

Coirault, C (reprint author), Sorbonne Univ, INSERM UMR S974, Ctr Res Myol, F-75013 Paris, France.; Zinn-Justin, S (reprint author), Univ Paris Saclay, Univ Paris South, Lab Struct Biol & Radiobiol, Inst Integrat Biol Cell,CEA,CNRS, F-91190 Gif Sur Yvette

CELLS, 2019; 8 (6):

Abstract

Emerin is a nuclear envelope protein that contributes to genome organization and cell mechanics. Through its N-terminal LAP2-emerin-MAN1 (LEM)-domain,......

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