Structure-based optimisation of non-steroidal cytochrome P450 17A1 inhibitors

Larsen, M; Hansen, CH; Rasmussen, TB; Islin, J; Styrishave, B; Olsen, L; Jorgensen, FS

Jorgensen, FS (reprint author), Univ Copenhagen, Dept Drug Design & Pharmacol, Jagtvej 162, DK-2100 Copenhagen, Denmark.

CHEMICAL COMMUNICATIONS, 2017; 53 (21): 3118

Abstract

Five new non-steroidal inhibitors for cytochrome P450 17A1 (CYP17A1) were identified by structure-based optimisation from a recently identified select......

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