Unraveling Determinants of Affinity Enhancement in Dimeric Aptamers for a Dimeric Protein

Manochehry, S; McConnell, EM; Li, YF

Li, YF (reprint author), McMaster Univ, Dept Biochem & Biomed Sci, 1280 Main St W, Hamilton, ON L8S 4K1, Canada.; Li, YF (reprint author), McMaster Univ, Dept Chem & Chem Biol, 1280 Main St W, Hamilton, ON L8S 4K1, Canada.

SCIENTIFIC REPORTS, 2019; 9 ():

Abstract

High-affinity aptamers can be derived de novo by using stringent conditions in SELEX (Systematic Evolution of Ligands by EXponential enrichment) exper......

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