Characterisation of the biflavonoid hinokiflavone as a pre-mRNA splicing modulator that inhibits SENP

Pawellek, A; Ryder, U; Tammsalu, T; King, LJ; Kreinin, H; Ly, T; Hay, RT; Hartley, RC; Lamond, AI

ELIFE, 2017; 6 ( ):

Abstract

We have identified the plant biflavonoid hinokiflavone as an inhibitor of splicing in vitro and modulator of alternative splicing in cells. Chemical s......

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