Accurate quantification of 5-Methylcytosine, 5-Hydroxymethylcytosine, 5-Formylcytosine, and 5-Carboxylcytosine in genomic DNA from breast cancer by chemical derivatization coupled with ultra performance liquid chromatography-electrospray quadrupole time o

Guo, MZ; Li, X; Zhang, LY; Liu, DT; Du, WC; Yin, DY; Lyu, N; Zhao, GY; Guo, C; Tang, DQ

Tang, DQ (reprint author), Xuzhou Med Coll, Jiangsu Key Lab New Drug Res & Clin Pharm, Xuzhou 221004, Jiangsu, Peoples R China.; Guo, C (reprint author), Zhejiang Univ, Sch Med, Affiliated Hosp 2, Canc Inst, Hangzhou 310009, Zhejiang, Peoples R China.

ONCOTARGET, 2017; 8 (53): 91248

Abstract

The DNA demethylation pathway has been discovered to play a significant role in DNA epigenetics. This pathway removes the methyl group from cytosine, ......

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