Human iPSC Glial Mouse Chimeras Reveal Glial Contributions to Schizophrenia

Windrem, MS; Osipovitch, M; Liu, ZS; Bates, J; Chandler-Militello, D; Zou, L; Munir, J; Schanz, S; Mccoy, K; Miller, RH; Wang, S; Nedergaard, M; Findling, RL; Tesar, PJ; Goldman, SA

Goldman, SA (reprint author), Univ Rochester, Med Ctr, Dept Neurol, Rochester, NY 14642 USA.; Goldman, SA (reprint author), Univ Rochester, Med Ctr, Ctr Translat Neuromed, Rochester, NY 14642 USA.; Goldman, SA (reprint author), Univ Copenhagen, Fac Hlth &

CELL STEM CELL, 2017; 21 (2): 195

Abstract

In this study, we investigated whether intrinsic glial dysfunction contributes to the pathogenesis of schizophrenia (SCZ). Our approach was to establi......

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