Subtype-specific block of voltage-gated K+ channels by mu-conopeptides

Leipold, E; Ullrich, F; Thiele, M; Tietze, AA; Terlau, H; Imhof, D; Heinemann, SH

Heinemann, SH (reprint author), Friedrich Schiller Univ Jena, Dept Biophys, Ctr Mol Biomed, Hans Knoll Str 2, D-07745 Jena, Germany.; Heinemann, SH (reprint author), Jena Univ Hosp, Hans Knoll Str 2, D-07745 Jena, Germany.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017; 482 (4): 1135

Abstract

The neurotoxic cone snail peptide mu-GIIIA specifically blocks skeletal muscle voltage-gated sodium (Na(V)1.4) channels. The related conopeptides mu-P......

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