BCL6 BTB-specific inhibition via FX1 treatment reduces Tfh cells and reverses lymphoid follicle hyperplasia in Indian rhesus macaque (Macaca mulatta)

Cai, YH; Watkins, MA; Xue, FT; Ai, Y; Cheng, HM; Midkiff, CC; Wang, XL; Alvarez, X; Poli, ANR; Salvino, JM; Veazey, RS; Montaner, LJ

Montaner, LJ (reprint author), Wistar Inst Anat & Biol, HIV 1 Immunopathogenesis Lab, 3601 Spruce St,Room 480, Philadelphia, PA 19104 USA.

JOURNAL OF MEDICAL PRIMATOLOGY, 2020; 49 (1): 26

Abstract

Background The BTB domain of B-cell lymphoma 6 (BCL6) protein was identified as a therapeutic target for B-cell lymphoma. This study compared the phar......

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