Can neurofilament lightchain as endpoint in Phase 2 derisk clinical disability worsening in Phase 3 in multiple sclerosis?

Collignon, O

Collignon, O (通讯作者),GSK, 980 Great West Rd, London TW8 9GS, England.

MULTIPLE SCLEROSIS AND RELATED DISORDERS, 2023; 80 ():

Abstract

Background: Neurofilament lightchain has been proposed as a Phase 2 endpoint in clinical trials for multiple sclerosis. We evaluated via simulations t......

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