The PTEN Conundrum: How to Target PTEN-Deficient Prostate Cancer

Turnham, DJ; Bullock, N; Dass, MS; Staffurth, JN; Pearson, HB

Pearson, HB (corresponding author), Cardiff Univ, Sch Biosci, European Canc Stem Cell Res Inst, Hadyn Ellis Bldg, Cardiff CF24 4HQ, Wales.

CELLS, 2020; 9 (11):

Abstract

Loss of the tumor suppressor phosphatase and tensin homologue deleted on chromosome 10 (PTEN), which negatively regulates the PI3K-AKT-mTOR pathway, i......

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