Interaction kinetics reveal distinct properties of conformational ensembles of three-repeat and four-repeat tau proteins

Hornakova, L; Sinsky, J; Janubova, M; Mederlyova, A; Ivanovova, NP; Piestansky, J; Kovac, A; Galba, J; Skrabana, R; Cehlar, O

Cehlar, O (通讯作者)，Slovak Acad Sci, Inst Neuroimmunol, Dubravska Cesta 9, Bratislava 84510, Slovakia.

FEBS LETTERS, 2022; 596 (9): 1178

Abstract

Tau protein is an intrinsically disordered protein. Its physiological state is best described as a conformational ensemble (CE) of metastable structur......

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