Hyaluronic acid-GPRC5C signalling promotes dormancy in haematopoietic stem cells

Zhang, YW; Mess, J; Aizarani, N; Mishra, P; Johnson, C; Romero-Mulero, MC; Rettkowski, J; Schonberger, K; Obier, N; Jacklein, K; Woessner, NM; Lalioti, ME; Velasco-Hernandez, T; Sikora, K; Wasch, R; Lehnertz, B; Sauvageau, G; Manke, T; Menendez, P; Walter, SG; Minguet, S; Laurenti, E; Gunther, S; Grun, D; Cabezas-Wallscheid, N

Cabezas-Wallscheid, N (通讯作者),Max Planck Inst Immunobiol & Epigenet, Freiburg, Germany.;Cabezas-Wallscheid, N (通讯作者),Ctr Integrat Biol Signalling Studies CIBSS, Freiburg, Germany.

NATURE CELL BIOLOGY, 2022; 24 (7): 1038

Abstract

Bone marrow haematopoietic stem cells (HSCs) are vital for lifelong maintenance of healthy haematopoiesis. In inbred mice housed in gnotobiotic facili......

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