Chemoenzymatic Synthesis of Tenofovir

Zdun, B; Reiter, T; Kroutil, W; Borowiecki, P

Borowiecki, P (通讯作者),Warsaw Univ Technol, Fac Chem, Dept Drugs Technol & Biotechnol, Lab Biocatalysis & Biotransformat, PL-00662 Warsaw, Poland.

JOURNAL OF ORGANIC CHEMISTRY, 2023; 88 (15): 11045

Abstract

We report on novel chemoenzymatic routes toward tenofovirusinglow-cost starting materials and commercial or homemade enzyme preparationsas biocatalyst......

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