Schlafen 5 as a novel therapeutic target in pancreatic ductal adenocarcinoma

Fischietti, M; Eckerdt, F; Blyth, GT; Arslan, AD; Mati, WM; Oku, CV; Perez, RE; Lee-Chang, C; Kosciuczuk, EM; Saleiro, D; Beauchamp, EM; Lesniak, MS; Verzella, D; Sun, LY; Fish, EN; Yang, GY; Qiang, WA; Platanias, LC

Platanias, LC (corresponding author), Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Chicago, IL 60611 USA.; Platanias, LC (corresponding author), Northwestern Univ, Dept Med, Feinberg Sch Med, Div Hematol Oncol, Chicago, IL 60611 USA.; Platanias, LC (corresponding author), Jesse Brown Vet Affairs Med Ctr, Dept Med, Chicago, IL 60612 USA.

ONCOGENE, 2021; 40 (18): 3273

Abstract

We provide evidence that a member of the human Schlafen (SLFN) family of proteins, SLFN5, is overexpressed in human pancreatic ductal adenocarcinoma (......

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